Any time someone is going to sticks needles into your face, there are going to be some side effects. However, for many, the benefits outweigh any temporary pain or discomfort that they may experience. That is why it is important to have a train professional to do the injection because you can avoid a lot of discomfort. So lets get to the point. What are the discomforts that one might experience getting botox injections? They are redness, itching, pain, bruising, and tenderness. Some people experience some mild headaches while others experience flu like symptoms immediately after the procedures.